منابع مشابه
Acting Locally but Thinking Globally
Sensor networks are, above all, embedded systems. The embedding of the nodes in physical space provides novel opportunities for wide-area sensing and monitoring that are unique to this technology and have generated a lot of excitement. At the same time, the very same dispersion in the environment generates a number challenges that need to be addressed, including power limitations because of unt...
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The phrase "think globally, act locally" was coined in the early 1970s and directed individuals to clean up their local environment with the ultimate goal of improving the health of the entire planet. Several recent studies indicate that similar considerations apply to the immune system, in which small numbers of leukocytes, such as pulmonary dendritic cells, can modify the local immune environ...
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Most diseases are local problems, whereas most treatments are systemic in nature. This simple, maddening imbalance remains one of the major causes of the ineffectiveness of our current pharmacological armamentarium. The notion of treating local disease with localized therapy has however emerged as one of the great promises of gene therapy. Two articles1,2 in this issue of Circulation Research e...
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of synaptic AMPA receptors, they find that activity-dependent changes in mEPSC amplitude are accompanied by changes in the accumulation of receptors at the synapse, and they demonstrate that the change in AMPA receptor number occurs through the activity-dependent What determines the strength of a synapse, and how regulation of receptor turnover. One of the most interest-does activity modify tha...
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ژورنال
عنوان ژورنال: Nature Climate Change
سال: 2009
ISSN: 1758-678X,1758-6798
DOI: 10.1038/climate.2009.11